Analyzing Monoclonal Antibody (mAbs) and mAb-Derived Therapeutics Using Native SEC-MS

Consumables Workflow Ordering Guide Analyzing Monoclonal Antibody (mAb) Fragments and Dimers Using Size Exclusion Chromatography (SEC) Low molecular weight (LMW) fragments and high molecular weight (HMW) dimers and aggregates can be formed from biotherapeutic proteins during drug development, storage, shipment,…

Consumables Workflow Ordering Guide Improving the Quality of Antibody Drug Conjugates by Orthogonal Analytical Methods Antibody Drug Conjugates Antibody-drug conjugates (ADCs) represent a new generation of targeted biotherapeutics that make up a rapidly growing segment of the drug discovery pipeline.…

Keep Your CQA Analysis Biocompatible from Start to Finish PEEK-lined columns and bio-inert supplies to complement the Agilent 1290 Infinity II bio LC system 2 Confidently Measure the Efficacy and Stability of Your Therapeutic Proteins with Agilent Consumables and InfinityLab…

Recommended starting conditions Column care and cleaning Parameter Value Column care Column AdvanceBio SEC 200 Å, 4.6 × 300 mm, 1.9 µm (p/n PL1580-5201) An increase in backpressure and a decrease in performance may occur over time. If the pressure…