The Ease of Use workflow — A simple way to set up MALDI Imaging measurements

High-speed MALDI-TOF/TOF imaging of mouse brain tissue performed on intact proteins and after on-tissue digestion The unique flexibility of MALDI-TOF/TOF systems facilitates tissue imaging of intact proteins as well as of tryptic peptides resulting from on-tissue digestion. While intact protein…

25 YEARS MALDI High-performance MALDI imaging analysis of on-tissue digested proteins in mammalian FFPE tissues using the Bruker rapifleX MALDI-TOF/TOF In this application note, we describe a workflow for MALDI Mass Spectrometry Imaging (MSI) of proteins from a variety of…

MALDI Mass Spectrometry Imaging Reveals Distinct Spatio-Molecular Phospholipid Distributions in Mouse Lungs While phospholipids play key roles in lung physiology and pathology, the complex composition and function of the lipidome in the lungs is poorly understood. We applied MALDI mass…

High Speed, High Lateral Resolution Lipid Imaging using a timsTOF fleX Changes in lipid profiles are known to occur in response to stress and disease. This structurally and functionally diverse class of compounds play important roles in various biological processes…