prm-PASEF®: enabling high-throughput, high sensitivity targeted proteomics

 prm-PASEF New for highly multiplexed targeted acquisition in clinical samples. TP470 a Samples were separated by nano-HPLC (nanoElute, Bruker Daltonics) on 250 mm pulled emitter columns (IonOpticks, Australia) with a 30 min gradient. Peptides were analyzed on a timsTOF…

PASEF™ on a timsTOF Pro defines new performance standards for shotgun proteomics with dramatic improvements in MS/MS data acquisition rates and sensitivity Trapped ion mobility spectrometry coupled with quadrupole time-of-flight mass spectrometry (timsTOF Pro) offers a unique dimension of characterization…

Parallel accumulation – serial fragmentation combined with data-independent acquisition (diaPASEF) The timsTOF Pro with diaPASEF enables deeper proteome coverage in a single 4D shotgun proteomics experiment, with highly reproducible qualitative and quantitative results – making it a near-ideal mass analyzer…

timsTOF Pro with PASEF and Evosep One: Maximizing throughput, robustness and analytical depth for shotgun proteomics The timsTOF Pro powered by PASEF enables sequencing speed of > 120 Hz, high sensitivity and robustness as well as an additional dimension of…