Proteomic changes in tissue samples of mouse gastric carcinoma: Label-free quantitation on the timsTOF fleX with PASEF

timsTOF MALDI Guided SpatialOMx Innovation with Integrity TIMS-MALDI MS MALDI Guided SpatialOMx The tumor microenvironment is a highly variable ecosystem, giving it an intrinsic temporal character. De-coding the cellular communication within the tumor microenvironment via label-free MALDI Imaging and x-omics…

Accurate Label-Free Protein Quantitation on the timsTOF Pro with 4D-Proteomics™ The timsTOF Pro platform brings together two unique technologies, namely Trapped Ion Mobility Spectrometry (TIMS) mode operation at the front-end and Parallel Accumulation Serial Fragmentation (PASEF [1]) for data acquisition.…

MALDI Guided SpatialOMx uncovers proteomic profiles in tumor subpopulations of breast cancer MALDI Guided SpatialOMx provides an excellent possibility to discover deep proteomics insights into heterogeneous tumor subpopulations by retaining the regiospecific information of an imaging technique. Abstract The timsTOF…

timsTOF Pro with PASEF and Evosep One: Maximizing throughput, robustness and analytical depth for shotgun proteomics The timsTOF Pro powered by PASEF enables sequencing speed of > 120 Hz, high sensitivity and robustness as well as an additional dimension of…