Reducing Compression Effects and Expanding the Multiplex Capabilities on a timsTOFPro with PASEF

Streamlined sample processing coupled to PASEF strategy for in-depth proteome quantification Katrin Hartinger, 1Nils Kulak, 2Nagarjuna Nagaraj, 1Fabian Hosp 1 PreOmics GmbH, Martinsried, Germany │ 2Bruker Daltonic GmbH, Bremen, Germany 1 Introduction Results 3 A 2500 1000 2000 100 700…

diaPASEF: label-free quantification of highly complex proteomes The timsTOF Pro with diaPASEF provides reproducible and accurate qualitative and quantitative results in complex proteomics samples – making it perfectly suited for data-independent acquisition approaches. Abstract Data-independent acquisition (DIA) promises reproducible and…

Accurate Label-Free Protein Quantitation on the timsTOF Pro with 4D-Proteomics™ The timsTOF Pro platform brings together two unique technologies, namely Trapped Ion Mobility Spectrometry (TIMS) mode operation at the front-end and Parallel Accumulation Serial Fragmentation (PASEF [1]) for data acquisition.…

Short gradients with Bruker’s nanoElute coupled to the timsTOF Pro with PASEF —Throughput and deep proteome measurements The nanoElute optimized for high throughput in chromatographic separation together with the timsTOF Pro powered by PASEF and the additional dimension of separation…