High-resolution Analysis of Charge Heterogeneity in Monoclonal Antibodies Using pH-gradient Cation Exchange Chromatography

Agilent-NISTmAb Charge Variant Analysis Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate profile, charge…

Agilent Biocolumns Charge Variant Analysis Application Compendium Contents Background 2 Getting Started 3 How to Guide - Ion-Exchange Chromatography for Biomolecule Analysis - 5991-3775EN 4 Featured Application Notes 22 Convenient Customization of Your Cation Exchange Analysis 5994-3257EN  22 How…

Charge Heterogeneity Analysis of Rituximab Innovator and Biosimilar mAbs Application Note Author Abstract Suresh Babu C.V. This Application Note describes the high-resolution separation of charge variants Agilent Technologies India Pvt. Ltd, of innovator and biosimilar rituximab using an Agilent 1260…

Analysis of Charge Heterogeneity in Rituximab Innovator and Biosimilar Monoclonal Antibodies Using Salt-Gradient Cation Exchange Chromatography Suresh Babu C.V., Salman Lateef Syed, Siji Joseph Agilent Technologies India Pvt. Ltd., Bangalore, India HPLC 2015 PSA-BIO-08 Introduction Results and Discussion Agilent Buffer…