Determination of Multiple Attributes of Monoclonal Antibodies

Application Note Pharma & Biopharma Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS Authors Gerd Vanhoenacker, Isabel Vandenheede, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) Kortrijk, Belgium Sonja Krieger, Sonja Schneider,…

MULTIDIMENSIONAL LC-MS PLATFORMS FOR STRUCTURE-FUNCTION CHARACTERIZATION OF THERAPEUTIC ANTIBODIES Jelle De Vos The Multidimensional Chromatography Workshop 2025, Liège 4 February 2025 The wonders of nature! RNA Protein DNA Cell 2 Monoclonal antibodies (mAbs) EVQLVESGGGLVQPGGSLRLSCAAS GFNIKDTYIHWVRQAPGKGLEW-- l mAbs have become a…

Biopharma Compendium Accelerate Your CQA Efficiency and Approach it with Multi-Attribute Methodology Breakthroughs to Increase the Efficiency of Critical Quality Attribute (CQA) Testing and Allow for a Multi- Attribute Method (MAM) Production of therapeutic monoclonal antibodies (mAbs) relies on living…

Consumables Workflow Ordering Guide Multi Dimensional HPLC Separation of Monoclonal Antibody Mixtures from Cell Culture Supernatants Therapeutic monoclonal antibodies (mAbs) come with structural complexity highly demanding towards analytics. Combining multiple analytical techniques on a system enables simultaneous multi-attribute analysis (MAA)…