Plasmid Isoform Separation and Quantification by Anion-Exchange Chromatography (AEX)

Application Note Slalom-Aided Anion Exchange Chromatography for Enhanced Analysis of Plasmid DNA Topological Impurities Abraham S. Finny, Fabrice Gritti, Szabolcs Fekete, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation, United States Published on July 23, 2025 Abstract Slalom-Aided Anion Exchange Chromatography…

Separation Solutions to Accelerate Next Generation Gene Therapy Development The therapeutics you are working on are cutting edge, complex and ultimately life-changing. Waters is here to help partner with you from bench to clinic through these challenges. COMMON ANALYTICAL QUESTIONS…

Application Note Separation and Size Assessment of dsDNA Fragments by Anion-Exchange Chromatography (AEX) Hua Yang, Stephan M. Koza, Weibin Chen Waters Corporation Abstract Reliably separating dsDNA species and assessing their sizes are important analytical tasks in the fields of cell…

Application Note Size and Purity Assessment of Single-Guide RNAs by Anion-Exchange Chromatography (AEX) Hua Yang, Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract Single-guide RNA (sgRNA) is a critical element in the CRISPR/Cas9 Technology for gene editing, the size…