Rapid Detection and Quantification of Selected Microsomal Substrates and Metabolites Using the Waters ACQUITY UPLC I-Class System and Xevo TQ-S micro

RADAR and PICS Compendium RADAR and PICS Compendium [ TABLE OF CONTENTS ] PAGE RADAR PICs RADAR and PICs CHEMICAL MATERIALS 5 Enantioseparation and Detection of Triazole Fungicides in Wheat Grain and Wheat Straw using the ACQUITY UPC2 System and…

METABOQUAN-R UPLC/MS/MS ANALYSIS OF 9 METABOLITES FOR CYTOCHROME P450 INHIBITION STUDIES IN A SINGLE ANALYTICAL RUN Billy Joe Molloy1, Catherine Pearson2, Phil Butler2, Robert Plumb1, Robert Riley2 1) Waters Corporation 2) Cyprotex RESULTS METHODS MetaboQuan-R is a high-throughput, generic UPLC…

APPLICATION NOTE Human spheroid-qualified hepatocytes 3D spheroid culture as a tool for studying drug metabolism Introduction The primary human hepatocyte (PHH) three-dimensional (3D) culture model developed by Thermo Fisher Scientific holds promise for disease modeling and functional studies. As the…

[ APPLICATION NOTEBOOK ] TARGETED METABOLOMICS AND LIPIDOMICS This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 A Validated Assay for the Quantification of Amino Acids in…