High Definition Multiple Reaction Monitoring: The Application of Quadrupole Ion Mobility Time-of-Flight Mass Spectrometry for Targeted Proteomics Studies

Targeted High Resolution Quantification with Tof-MRM and HD-MRM Nick Tomczyk, Alistair Wallace, Keith Richardson, Arkadiusz Grzyb, Jason Wildgoose G OA L Tof-MRM and HD-MRM workflows enable users to To enable routine quantification at very low limits while providing the sensitivity…

High Definition Data Directed Analysis (HD-DDA) Nick Tomczyk, Alistair Wallace, Keith Richardson, Arkadiusz Grzyb, and Jason Wildgoose G OA L High Definition Data Directed Analysis provides the To improve routine discovery workflows with High Definition Data Directed Analysis (HD-DDA), a…

ACQUISITION MODE CHARACTERIZATION FOR THE QUANTITATIVE AND QUALITATIVE ANALYSIS OF CROSS-LINKED PEPTIDES BY TARGETED AND UNTARGETED LC-IM-MS Hannah Britt1,2, Suniya Khatun1,2, Abubakar Hatimy1,2, Jonathan P Williams3, Christopher Hughes3, Tristan Cragnolini1,2, Nathanael Page4, Konstantinos Thalassinos1,2 and Johannes PC Vissers3 1 Institute…

Assay for Identification and Quantification of Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm: An Inter-Laboratory Study Catalin E. Doneanu, Malcolm Anderson, Brad J. Williams, Matthew A. Lauber, Asish Chakraborty, and Weibin Chen Waters Corporation, Milford,…