Application note | 004167 Biopharma Charge variant analysis of cysteine-linked antibody-drug conjugates using an online multiple heart-cut 2DSCX-SEC-LC HRAM MS approach Authors Application benefits Xuepu Li¹, Xiaoxi Zhang¹, Maria Grübner², • The online multiple heart-cut two-dimensional liquid chromatography (2D-LC) system…
Klíčová slova
charge, polatuzumab, variants, vanquish, vedotin, heterogeneity, pump, mass, fraction, scientific, thermo, sec, backflush, oxidation, antibody