Rapid Analysis of Cyclosporine A, Everolimus, Sirolimus, and Tacrolimus Drugs in Whole Blood Using an Agilent Triple Quadrupole LC/MS/MS System with Automated Online Sample Cleanup

A Robustness Study for the Agilent 6470 LC-MS/MS Mass Spectrometer Application Note Clinical Research Authors Abstract Linda Côté, Siji Joseph, Sreelakshmy Long-term robustness studies were conducted on the Agilent 6470 LC-MS/MS Menon, and Kevin McCann mass spectrometer. Four common immunosuppressants…

Methods Calibrators Calibrators containing cyclosporin A, everolimus, sirolimus, and tacrolimus in whole blood were purchased from Chromsystems Instruments & Chemicals GmbH (TABLE 1). Evaluation of Benchtop Quadrupole Orbitrap Ultra-High-Resolution Mass Spectrometer in Rapid Quantitative Analysis of Immunosuppressant Evaluation of Benchtop…

TECHNICAL NOTE 66003 Quantification of immunosuppressants in human blood by LC-HRAM mass spectrometry for clinical research Authors: Claudio De Nardi1, Anke Deden2, Anne Behrens2, Sebastian Berger2 Thermo Fisher Scientific GmbH, Dreieich, Germany 1 RECIPE Chemicals + Instruments GmbH, Munich, Germany…

Simultaneous Analysis of Tacrolimus, Sirolimus, Everolimus, and Cyclosporin A in Whole Blood Using the Agilent RapidFire High-Throughput Mass Spectrometry System Application Note Clinical Research Authors Introduction Kari E. Schlicht and Vaughn P. Miller Agilent Technologies, Inc. Wakefield, MA USA In…