Bypassing LC System Passivation Requirements Using ACQUITY PREMIER with MaxPeak HPS Technology for the Recovery of a Phosphorylated Peptide

Application Note Improving Recovery and Quantitation of Oligonucleotide Impurities Using ACQUITY PREMIER with MaxPeak HPS Technology Brooke M. Koshel, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Ion-pair reversed-phase chromatography is a commonly used technique for the separation of…

Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology Analytical Solutions Using MaxPeak High Performance Surfaces (HPS) Technology for Biopharmaceutical Therapeutics Biopharmaceutical therapeutics have consistently been the fastest growing segment within the pharmaceutical space and require advances…

Application Note Enhancing Phosphopeptide Quantitation using PREMIER Peptide CSH C18 Columns Jennifer M. Nguyen, Susan C. Rzewuski, Matthew A. Lauber Waters Corporation Abstract During LC separations, many analytes, especially those bearing a negative charge, can adsorb to electrondeficient metal oxide…

Application Note Increasing Chromatographic Performance of Acidic Peptides in RPLC-MS-based Assays with ACQUITY PREMIER featuring MaxPeak HPS Technology Robert E. Birdsall, Jacob Kellet, Samantha Ippoliti, Nilini Ranbaduge, Henry Shion, Ying Qing Yu Waters Corporation Abstract Metal-ion mediated adsorption of analytes…