Characterizing Low Abundance Monoclonal Antibody PTMs Using UNIFI Scientific Information System Peptide Mapping DDA Workflow

[ APPLICATION NOTE ] Automated Protein Modification Characterization of the Intact and Subunit NIST Monoclonal Antibody Reference Standard with Waters UNIFI Scientific Information System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…

A Streamlined Data Dependent Acquisition (DDA) Peptide Mapping Workflow for Characterizing Therapeutic Proteins Using the Biopharmaceutical Platform Solution with UNIFI Liuxi Chen and Ying Qing Yu Waters Corporation, Milford, MA, USA A P P L I C AT I O…

[ APPLICATION NOTE ] Peptide Mapping with Higher Confidence: The Application Capability of IMS QTof Mass Spectrometry with Four-dimension (4D) Peak Detection (RT, m/z, intensity, and CCS values) Jing Fang, Ying Qing Yu, Min Du, and Weibin Chen Waters Corporation,…

BIOPHARMACEUTICAL PLATFORM SOLUTION Key Applications TABLE OF CONTENTS Biopharmaceutical Platform Solution with UNIFI: Key Applications Intact Protein MS Analysis I Peptide Mapping I Released Glycan Analysis I Bioseparations Biotherapeutic proteins – such as monoclonal antibodies (mAbs), biosimilars, and antibody drug…