Peptide Mapping with Higher Confidence:The Application Capability of IMS QTof Mass Spectrometry with Four-dimension (4D) Peak Detection (RT, m/z, intensity, and CCS values)

[ APPLICATION NOTE ] Integrating Ion Mobility into Routine Drug Metabolite Identification Studies Using the Vion IMS QTof Mass Spectrometer Jayne Kirk, 1 Russell Mortishire-Smith, 1 and Mark Wrona 2 1 Waters Corporation, Wilmslow, UK 2 Waters Corporation, Milford, MA,…

[ APPLICATION NOTE ] Somatostatin Analogue Catabolite Screening and Identification Using Vion IMS QTof with WebMetabase Mark D. Wrona, 1 Jayne M. Kirk, 4 Ismael Zamora, 2 Tatiana Radchenko, 2 Anna Escola, 3 Antoni Riera, 3 Russell J. Mortishire-Smith4 Waters…

[ APPLICATION NOTE ] Metabolite Identification of Complex Cyclic Peptides Using WebMetabase, Ion Mobility-Enabled DIA, and Product Ion Confirmation Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ Ability to screen metabolism from The incorporation of unnatural amino acids,…

[ APPLICATION NOTE ] Building a Collision Cross Section Library of Pharmaceutical Drugs Using the Vion IMS QTof Platform: Verification of System Performance, Precision and Deviation of CCS Measurements Yun Wang Alelyunas, Kerri Smith, Gareth Cleland, Russell Mortishire-Smith, and Mark…