Confident Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap-Mass-Spectrometer-Based GC-MS

Aplikace | 2016 | Thermo Fisher ScientificInstrumentace

GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap

Zaměření

Farmaceutická analýza, Materiálová analýza

Výrobce

Thermo Fisher Scientific

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Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based GC-MS

2016|Thermo Fisher Scientific|Postery

Dominic Roberts1, Andrew Feilden2, Richard Barlow2, Jason Cole1, Alexander Semyonov1, Kyle D’Silva1, and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK; 2Smithers Rapra, Shawbury, UK. Poster Note 64741 Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based…

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ISCC 2016: Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap based GC-MS

2016|Thermo Fisher Scientific|Postery

and accurate differential analysis to be performed to isolate unique features in extracts. Routine mass resolution of 60,000 FWHM and consistent sub-ppm mass accuracy ensures selective and confident compound detection and identification. POSTER NOTE Introduction The investigation of potentially toxic…