Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based GC-MS

Postery | 2016 | Thermo Fisher Scientific | ASMSInstrumentace

GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap

Zaměření

Farmaceutická analýza

Výrobce

Thermo Fisher Scientific

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ISCC 2016: Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap based GC-MS

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and accurate differential analysis to be performed to isolate unique features in extracts. Routine mass resolution of 60,000 FWHM and consistent sub-ppm mass accuracy ensures selective and confident compound detection and identification. POSTER NOTE Introduction The investigation of potentially toxic…

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mass, octanoate, closure, extractables, deconvoluted, packaging, migrate, elevated, each, shown, scan, identification, figure, chromatograms, container

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Dominic Roberts,1 Andrew Feilden,2 Richard Barlow,2 Kyle D’Silva,1 and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK 2 Smithers Rapra, Shawbury, UK Key Words Extractables and Leachables, Q Exactive GC, Orbitrap mass spectrometry, differential analysis, unknown identification, container closure system,…