[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…
Application Note Using Targeted MRM MS Imaging With DESI to Visually Localize Isobaric And/or Low Abundance Lipids Emmanuelle Claude Waters Corporation Abstract DESI technique ionizes small molecules such as lipids, efficiently directly from surfaces such as tissue sections, without any…
TARGETED DESI IMAGING MS OF DRUG DISTRIBUTION AND DRUGINDUCED LIVER INJURY (DILI) METABOLITES FROM METHAPYRILENE IN THE MALE WISTAR RAT Anthony Midey,1 Emmanuelle Claude,2 Lisa Reid,2 Bindesh Shrestha,1 Steven K Lai,1 Ian D Wilson,3 Robert S Plumb,1 and Roy Martin1…
SPATIAL MAPPING OF LIPIDS AND NEUROTRANSMITTER IN RAT BRAIN SECTIONS USING DESI ION MOBILITY MASS SPECTROMETRY Roy Martin1, Anthony J. Midey1, Hernando J. Olivos1, Emmanuelle Claude2, Bindesh Shrestha1 1 Waters Corporation, Milford, MA, USA and 2 Waters Corporation, Wimslow, United…
