Determination of Genotoxic Nitrosamine Impurity in Bumetanide API and Tablets Using the Agilent 6470 Triple Quadrupole LC/MS

Application Note Pharmaceuticals Quantitation of N-Nitroso Hydrochlorothiazide in LosartanHydrochlorothiazide Tablets Using the Agilent 6495D Triple Quadrupole LC/MS/MS System Authors Saikat Bhattacharya, Prasanth Joseph, Vivek Dhyani, and Saikat Banerjee Agilent Technologies, Inc. Abstract Losartan and hydrochlorothiazide (HCTZ) tablets combine an angiotensin…

Application Note Pharmaceuticals Quantitation of N-Nitroso Moxifloxacin in 400 mg Moxifloxacin Tablet Formulation Using the Agilent 6495D triple quadrupole LC/MS/MS system Authors Abstract Saikat Bhattacharya, Prasanth Joseph, Vivek Dhyani, and Saikat Banerjee Agilent Technologies, Inc. N-Nitroso moxifloxacin, a nitrosamine drug…

Application Note Pharmaceuticals Quantitation of N-Nitroso N-Desmethyl Diphenhydramine in Diphenhydramine HCl API Using the Agilent 6475A triple quadrupole LC/MS system Authors Abstract Prasanth Joseph, Sandeep Choudhary, Vivek Dhyani, Saikat Banerjee, and Kannan Balakrishnan Agilent Technologies, Inc. A highly specific, sensitive,…

Application Note Pharmaceuticals Quantitation of N-Nitroso Nebivolol in Nebivolol Tablet Formulation Using an Agilent 6495D triple quadrupole LC/MS system Authors Abstract Prasanth Joseph, Saikat Bhattacharya, Vivek Dhyani, and Saikat Banerjee Agilent Technologies, Inc. N-Nitroso Nebivolol, a nitroso drug substance-related impurity…