HRMS System Check for Intact Protein Quantification

TANDEM QUADRUPOLE MS FOR THE QUANTIFICATION OF MONOCLONAL ANTIBODY SUBUNIT LIGHT CHAINS IN PLASMA Caitlin M. Dunning, Mary E. Lame, and Mark D. Wrona Waters Corporation, Milford, MA, USA INTRODUCTION CHROMATOGRAPHY MASS SPECTROMETRY 5 µg/mL Adalimumab - 10µL - Rep…

[ APPLICATION NOTE ] Automated Protein Modification Characterization of the Intact and Subunit NIST Monoclonal Antibody Reference Standard with Waters UNIFI Scientific Information System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…

[ APPLICATION NOTE ] Triple Quadrupole Mass Spectrometry (Xevo TQ-XS) for the Quantification of Monoclonal Antibody Light Chains in Plasma Caitlin M. Dunning, Mary Lame, and Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Fast, reproducible, and…

[ APPLICATION NOTE ] How to Maximize Bioanalytical Performance of Fc-Fusion Proteins: Practical Sample Preparation and LC-MS/MS Workflows for Dulaglutide Quantification from Plasma Caitlin M. Dunning and Mark D. Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ ■…