Auto•Blend Plus Technology for Ion-Exchange Chromatography Method Development and Robustness Testing

[ APPLICATION NOTE ] Development of Monoclonal Antibody Charge Variant Analysis Methods Using a BioResolve SCX mAb Column Hua Yang, Bill Warren, and Stephan Koza Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Method development parameters for cation Charge heterogeneity…

[ APPLICATION NOTE ] Method Development Tools for More Efficient Screening of Biopharmaceutical Method Conditions Using the ACQUITY Arc Bio System Part 2 of 2: Screening SEC and IEX Conditions in a Single Experiment Brooke M. Koshel, Robert E. Birdsall,…

[ TECHNOLOGY BRIEF ] Charge Variant Analysis of Infliximab on the Alliance, ACQUITY Arc Bio, and ACQUITY UPLC H-Class Bio Liquid Chromatography Systems Using a Quaternary pH Gradient Corey E. Reed, Stephan M. Koza, and Weibin Chen, Waters Corporation, Milford,…

Developing Robust and Efficient IEX Methods for Charge Variant Analysis of Biotherapeutics Using ACQUITY UPLC H-Class System and Auto • Blend Plus Robert Birdsall, Thomas Wheat, and Weibin Chen Waters Corporation, Milford, MA, USA A P P L I C…