Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies

Biopharma Compendium Accelerate Your CQA Efficiency and Approach it with Multi-Attribute Methodology Breakthroughs to Increase the Efficiency of Critical Quality Attribute (CQA) Testing and Allow for a Multi- Attribute Method (MAM) Production of therapeutic monoclonal antibodies (mAbs) relies on living…

Application Note Biopharma/Pharma Peptide Mapping and Quantitation of Oxidation and Deamidation in Monoclonal Antibodies Author Yulan Bian Agilent Technologies, Inc. Abstract This application note demonstrates an integrated workflow of peptide mapping and quantitation of chemical-induced oxidation and deamidation in monoclonal…

Enhancing The Quality Of Peptide Mapping Separation For The Analysis Of PTM Application Note Biotherapeutics and Biosimilars Author Introduction Suresh Babu C.V. Post-translational modifications (PTMs) on proteins such as monoclonal antibodies (mAbs) are critical quality attributes (CQAs) that define the…

Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Author Introduction Ravindra Gudihal Monoclonal antibodies (mAbs) are becoming one of the important classes of…