High Sensitivity Identification of Drug Metabolites with Increasing Ionization Efficiency using A Novel LC-ESI Interface and Q-TOF

A P P LICAT ION SOLUT IONS FO R M ETABOLIT E IDENT IFICAT ION A P P L I C AT I O N S O L U T I O N S F O R M E TA…

Microflow Chromatography: A Key to More Sensitive Met ID Use of OptiFlow® Turbo V Source with Triple TOF® 6600+ System to Identification and Characterization of Small Molecule Metabolites Carmai Seto1, Alina Dindyal-Popescu1, Rolf Kern2 1 SCIEX, Concord, Ontario, 2SCIEX, Redwood…

Use of Charged Aerosol Detection as an Orthogonal Quantification Technique for Drug Metabolites in Safety Testing (MIST) Christopher Crafts, Bruce Bailey, Marc Plante, John Waraska, Paul Gamache, and Ian Acworth ESA—A Dionex Company, Chelmsford, MA, USA Abstract INTRODUCTION The publication…

Identification of novel pyrimidine ring cleavage metabolites of Buspirone via Spectral Similarity correlation score Kirsten Hobby, Alan Barnes, Neil Loftus Shimadzu, Manchester, UK 1:Introduction 3-2: Proposed metabolite structure's 222 MS2 Buspirone is an anxiolytic psychoactive drug of the azapirone chemical…