Optimized Workflow for Structure Elucidation of Pharmaceutically Relevant Extractables and Leachables

Enhanced Metabolite Identification using Orbitrap™ Tribrid Mass Spectrometer Shuguang Ma, Ph.D. Drug Metabolism and Pharmacokinetics Genentech, Inc. Thermo Fisher Scientific 2018 ASMS Breakfast Workshop, June 04, 2018 Outline  Introduction  Orbitrap ID-X with AcquireX Algorithm and Workflow  Case…

Enhanced Metabolite Identification Using Orbitrap Tribrid Mass Spectrometer Kate Comstock1, Shuguang Ma2, Caroline Ding1, Yan Chen1, Seema Sharma1 1Thermo Fisher Scientific, River Oaks Pkwy, San Jose, CA USA INSTRUMENT and METHOD 90 Figure 1. Orbitrap ID-X Ready-Made Method Template 80…

Improved Orbitrap Tribrid MS for Pharmaceutical Impurity Identification Fenghe Qiu1, Kate Comstock2, Seema Sharma2, Graeme McAlister2 1Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA 2Thermo Fisher Scientific, San Jose, CA, USA OVERVIEW DATA ACQUISITION USING AcquireX Purpose: Improving pharmaceutical impurity identification…

Search for What’s Missing: Unknown Compound Characterization Using LC-MS Kate Comstock Sr. Marketing Specialist, Pharma/Biopharma Marketing The world leader in serving science Small Molecule Structure Analysis Small molecule structure analysis encompasses broad applications: Pharmaceutical, metabolomics, food & environmental, clinical, forensic,…