Rapid Analysis of Genotoxic Nitrosamines by HPLC-MS/MS

Application Note Biopharma Quantitative Analysis of Nitrosamine Impurities in Synthetic Oligonucleotides Using the Agilent 6495D triple quadrupole LC/MS system Author Abstract Yulan Bian Agilent Technologies, Inc. Nitrosamines are genotoxic impurities of significant concern in pharmaceuticals due to their carcinogenic potential.…

Application Note Determination of Nitrosamine Impurities Using the Agilent 6495D Triple Quadrupole LC/MS System Authors Abstract Lee Bertram and Linfeng Wu Agilent Technologies, Inc. Nitrosamine impurities are byproducts produced in trace amounts during the manufacture of pharmaceutical drugs. These impurities…

Application Note Pharma/Biopharma Determination of Nitrosamine Impurities Using the Agilent 6475 Triple Quadrupole LC/MS System Authors Linfeng Wu and Lee Bertram Agilent Technologies, Inc. Santa Clara, CA, U.S. Shan-An Chan Agilent Technologies, Inc. Taiwan Abstract Nitrosamine impurities are by-products that…

Poster Reprint ASMS 2023 Poster number TP 732 Improvement Upon a Multi-Residue Method for Nitrosamine Analysis in Losartan Drug Product Using an Enhanced LC/MS/MS System Bertram Lee1, Linfeng Wu1, Shan-An Chan2 and Winnie Huang3 1Agilent Technologies, Inc., Santa Clara, CA,…