Native State Charge Variant Analysis of Commercialized Monoclonal Antibodies in Minutes

Subunit charge variant characterization in the native state Fang Wang1 Zoe Zhang2, 1SCIEX Brea, CA (USA) 2 SCIEX Redwood City, CA (USA), Monoclonal antibody (mAb) therapeutics often contain charge variants that arise from a wide array of post-translational modifications (PTM),…

Capillar y electrophoresis k its Kits to meet the challenges of today with the flexibility for tomorrow The Power of Precision Quantify size and purity, either reduced or non-reduced 390953 SDS-MW Analysis Kit / A10663 IgG Purit y /Heterogeneit y…

Charge Heterogeneity Analysis in as little as 5 Minutes SCIEX CZE Rapid Charge Variant Analysis Kit Charge variant analysis has never been easier. In under 5 minutes of separation time on the PA 800 Plus, the CZE (Capillary Zone Electrophoresis)…

Charge Heterogeneity Analysis of Intact Infliximab Using CESI-MS and Neutral OptiMS Cartridge Fang Wang1, Tingting Li1, Esme Candish2 1 SCIEX, Brea, CA; 2SCIEX, Framingham, MA; Key Features • Capillary zone electrophoresis (CZE) separation and Mass spectrometric (MS) identification of charge…