Separation and Analysis of TCA Cycle Analytes by Mixed-Mode Chromatography Coupled with Mass Spectrometry

Ion Pairing Free Mixed-Mode Chromatography for the Separation and Measurement of TCA Cycle Metabolites in Urine Samples of Breast Cancer Patients Kerri M Smith, Giorgis Isaac, Suraj Dhungana and Paul D. Rainville Waters Corporation, Milford MA RESULTS and DISCUSSION Additional…

Improving sensitivity for the quantification of TCA cycle analytes in human plasma by the ACQUITY™ Premier system solution Kerri M Smith, Paul. D Rainville Waters Corporation, Milford, MA, USA LC System: ACQUITY™ Premier LC MS: XEVO TQ-Smicro, ESI negative Column:…

Separation and Analysis of Low Molecular Weight Organic Acid Metabolites by Mixed-Mode Chromatography Coupled to Mass Spectrometry Kerri M. Smith, Paul D. Rainville Waters Corporation, Milford, MA USA INTRODUCTION METHODS The components of the Tricarboxylic acid (TCA) cycle are small…

[ TECHNOLOGY BRIEF ] Separation and Detection of TCA Cycle Metabolites and Related Compounds in Human Urine by UPLC-MS/MS for Clinical Research Kerri M. Smith, Robert S. Plumb, and Paul D. Rainville Waters Corporation, Milford, MA, USA A new method…