Ion Pairing Free Mixed-Mode Chromatography for the Separation and Measurement of TCA Cycle Metabolites in Urine Samples of Breast Cancer Patients

Improving sensitivity for the quantification of TCA cycle analytes in human plasma by the ACQUITY™ Premier system solution Kerri M Smith, Paul. D Rainville Waters Corporation, Milford, MA, USA LC System: ACQUITY™ Premier LC MS: XEVO TQ-Smicro, ESI negative Column:…

[ APPLICATION NOTE ] Separation and Analysis of TCA Cycle Analytes by Mixed-Mode Chromatography Coupled with Mass Spectrometry Kerri M. Smith and Paul Rainville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ INTRODUCTION A reproducible LC-MS method for the…

Application Note Improved Analytical Sensitivity and Chromatographic Peak Shape for the Quantification of TCA Cycle Analytes in Human Plasma using the ACQUITY PREMIER System Solution Kerri M. Smith, Paul D. Rainville Waters Corporation For research use only. Not for use…

[ TECHNOLOGY BRIEF ] Separation and Detection of TCA Cycle Metabolites and Related Compounds in Human Urine by UPLC-MS/MS for Clinical Research Kerri M. Smith, Robert S. Plumb, and Paul D. Rainville Waters Corporation, Milford, MA, USA A new method…