Analysis of Cyclosporine, Everolimus, Sirolimus, and Tacrolimus in Whole Blood for Clinical Research

Simultaneous Analysis of Tacrolimus, Sirolimus, Everolimus, and Cyclosporin A in Whole Blood Using the Agilent RapidFire High-Throughput Mass Spectrometry System Application Note Clinical Research Authors Introduction Kari E. Schlicht and Vaughn P. Miller Agilent Technologies, Inc. Wakefield, MA USA In…

® DOSIMMUNE : Fully automated analysis of immunosuppressant drugs in whole blood using stable isotope labeled internal standards Fanny Dayot1, Jean-François Hoeffler1, Toshikazu Minohata1,2 1 ALSACHIM SAS, Illkirch, France, 2 Shimadzu Corporation, Kyoto, Japan 1. Introduction 3. Result and discussion…

Application Note Clinical Research Ultrafast Quantitation of Immunosuppressant Drugs in Whole Blood by Agilent 6475 LC/MS Author Udi Jumhawan Agilent Technologies, Inc. Abstract An ultrafast, 2.5-minute quantitation method using liquid chromatography/mass spectrometry (LC/MS) for four immunosuppressant drugs was established using…

Methods Calibrators Calibrators containing cyclosporin A, everolimus, sirolimus, and tacrolimus in whole blood were purchased from Chromsystems Instruments & Chemicals GmbH (TABLE 1). Evaluation of Benchtop Quadrupole Orbitrap Ultra-High-Resolution Mass Spectrometer in Rapid Quantitative Analysis of Immunosuppressant Evaluation of Benchtop…