Consistent Size-based Separations Across LC Systems with SEC 125 Å MaxPeak Premier Columns

[ SEC COLUMN TECHNOLOGY ] Solutions for Aggregate and Fragment Analyses Size-exclusion chromatography (SEC) is a powerful technique for aggregate and fragment analysis in the research, development, and manufacturing of biotherapeutic proteins, as well as viral vectors. Important Considerations in…

Application Note Advancing Analysis of Covalent High Molecular Weight Insulin With ACQUITY® Premier SEC 125 Å Columns Philip Wuthrich, Stephan M. Koza, Steve Shiner Waters Corporation Abstract Here we perform denaturing SEC analysis of human insulin with an ACQUITY Premier…

[ CARE AND USE MANUAL ] XBridge Premier Protein SEC 250 Å, 2.5 µm Columns CONTENTS I. INTRODUCTION Thank you for choosing a Waters™ SEC Column. The XBridge™ I. INTRODUCTION II. SEC ANALYSIS OF PROTEIN AGGREGATES, MONOMERS, AND FRAGMENTS…

Application Note Rapid Size Variant Analysis of Monoclonal Antibodies Using UPLC™ and HPLC Compatible MaxPeak™ Premier Protein SEC Columns Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract High-throughput and rapid size-exclusion chromatography (SEC) methods can be useful to support…