Effects on Endogenous Metabolites Following the Administration of Methapyrilene: A Data-Dependent Acquisition Workflow Using the Xevo™ MRT Mass Spectrometer

Application Note Investigating Drug Metabolism of Methapyrilene Within a Rat Model Using a Data Dependent Acquisition Workflow with the Xevo MRT Mass Spectrometer Lee A. Gethingsa, Richard Locka, Susan Abatiellob, Jennifer Seymourc, Terri Sosienskic, Jeff Finchc, Jeremy Feltonc , Donald…

Application Note A Rapid Approach to Metabolite Identification Using Xevo MRT Mass Spectrometer and MassMetaSite Software Richard Lock, Robert Plumb, Lee Gethings Waters Corporation, United States Published on November 25, 2025 Abstract Metabolite identification is a critical component of drug…

CONVERSION AND INTEGRATION OF OMICS DATA FROM A PROTOTYPE, BENCHTOP MULTI-REFLECTING TIME-OF-FLIGHT (MRT) PLATFORM WITH THIRD-PARTY INFORMATIC WORKFLOWS Lee A. Gethings, Ian Morns, Pete Reay, Simon Jones, Nyasha Munjoma, Jayne Kirk, Richard Lock Waters Corp., Wilmslow, Cheshire, United Kingdom OMIC…

Application Note Metabolomics Workflow using a Xevo™ MRT Mass Spectrometer Lisa Reid, Matthew E. Daly, Lee A. Gethings, Jayne Kirk Waters Corporation Abstract We demonstrate the acquisition and data processing to identify and pathway profile a typical metabolomic study acquired…