Investigating Drug Metabolism of Methapyrilene Within a Rat Model Using a Data Dependent Acquisition Workflow with the Xevo MRT Mass Spectrometer

Application Note A Rapid Approach to Metabolite Identification Using Xevo MRT Mass Spectrometer and MassMetaSite Software Richard Lock, Robert Plumb, Lee Gethings Waters Corporation, United States Published on November 25, 2025 Abstract Metabolite identification is a critical component of drug…

Application Note Effects on Endogenous Metabolites Following the Administration of Methapyrilene: A Data-Dependent Acquisition Workflow Using the Xevo™ MRT Mass Spectrometer Lee A. Gethings,a Susan Abatiello,b Jennifer Seymour,c Terri Sosienski,c Jeff Finch,c Jeremy Felton,c Donald Laudicina,c Richard Lock,a Robert S.…

Application Note Constant Neutral Loss, Precursor Ion Scanning, Product Ion Scanning in Support of DMPK Studies Using waters_connect for Quantitation Software Solution and Xevo TQ Absolute XR Mass Spectrometer Robert S. Plumb, Nikunj Tanna Waters Corporation, United States Published on…

Application Note Mining Drug Metabolite Data Using waters_connect™ LC-MS Toolkit, Mass Fragment and Tandem Quadrupole LCMS/MS Robert Plumb, Peter Christensen, Nikunj Tanna Waters Corporation, United States Published on December 05, 2025 Application Brief This is an Application Brief and does…