Implementation of Electron-transfer dissociation (ETD) and Electron-transfer/higher-energy collision dissociation (EThcD) on a modified Orbitrap hybrid MS

Technical note | 004377 Mass spectrometry Advancing phosphorylation, ADMA, and O-GlcNAc PTM analysis with HCD and EThcD on the Orbitrap Excedion Pro mass spectrometer Authors Goal Mikayla Shanafelt1, Brett Larsen2, Demonstrate fast and sensitive performance of the Thermo Scientific™ Orbitrap™…

In-depth peptide mapping of biopharmaceuticals using an electron-transfer/higher-energy collision dissociation (EThcD) implemented on a modified Orbitrap hybrid MS Reiko Kiyonami1, Cong Wang2, Peter Krueger2, Roberto Gamez1, Heiner Koch2, Min Du1 1Thermo Fisher Scientific, Lexington, MA; 2Thermo Fisher Scientific, Bremen, Germany…

The universal Orbitrap instrument - from metabolomics over targeted proteomics to native analyses Jan-Peter Hauschild, Christian Thoeing, Peter Krueger, Erik Couzijn, Andreas Kuehn, Hartmut Kuipers, Matthias Lange, Bastian Reitemeier, Adrian Schuetz, Amelia Corinne Peterson, Nicole Zehethofer, Yovany Cordero Hernandez, Markus…

Complete characterization of KADCYLA using a new Orbitrap Excedion Pro BioPharma hybrid mass spectrometer with electron-transfer/higher-energy collision dissociation (EThcD) fragmentation Xiaoxi Zhang1, Roberto Gamez2, Reiko Kiyonami3, Cong Wang4, Peter Krueger4, Heiner Koch4, Min Du3 1 Thermo Fisher Scientific, Shanghai, China;…