Accelerating Discovery: High-Throughput Single-Cell Proteomics with Rapid Analysis and Deep Protein Coverage

US HUPO 2024 Ultra-high sensitive Single Cell Proteomics on the timsTOF Ultra A Shourjo Ghose1, Christoph Krisp2, Anjali Seth3, David Hartlmayr3, Guilhem Tourniaire3, Léo Laboubi4, Markus Lubeck2 and Gary Kruppa5 C Autosampler needle dried peptides 1 Bruker Scientific LLC., Billerica,…

Short gradients with Bruker’s nanoElute coupled to the timsTOF Pro with PASEF —Throughput and deep proteome measurements The nanoElute optimized for high throughput in chromatographic separation together with the timsTOF Pro powered by PASEF and the additional dimension of separation…

Elevating Precision in –Omics Applications: A Breakthrough with Monolithic Silica Columns USHUPO 2024 1Bruker Daltonics Inc., Billerica, USA 2Kyoto University, Kyoto, Japan 3Bruker Japan K.K., Yokohama, Japan 4Bruker Switzerland, Fallanden, Switzerland Introduction Single-cell proteomics is one of several scientific domains…

Ultra-high sensitivity proteomics on the timsTOF SCP The sensitivity of the mass spectrometer plays a crucial role in analyzing low input samples and single cell proteomics. Abstract The timsTOF Pro platform, introduced in 2017, already featured a sensitivity boost from…