Isocratic Separation of Six Cardiac Antiarrhythmic Drugs (Beta-Blockers) on a Thermo Scientific™ Acclaim™ 120 C8 Column

Ken Meadows, Thermo Fisher Scientific, Runcorn, UK Key Words Vanquish, Accucore, beta blockers, beta antagonists, UHPLC, solid core, fused core, sotalol, pindolol, timolol, acebutolol, metoprolol, esmolol, celiprolol, oxprenolol, labetalol, propranolol, betaxolol, carvidilol, nebivolol, penbutalol Goal To demonstrate the advantages of…

Acclaim columns overview Columns for challenging separation needs Broad range of HPLC and UHPLC columns Phenyl-1 C30 Mixed-Mode WAX-1 Mixed-Mode WCX-1 Organic acid Surfactant Plus AmG C18 Explosives E2 M Mixed-Mode HILIC-1 ix ed -m Trinity P1 od e Carbamate…

Application note | 003910 Pharma Liquid chromatography – high-resolution mass spectrometry method for determination of NDSRI in six beta-blocker drug substances Authors Application benefits Varun Khali1, Manoj Kushwaha1, • A single high-resolution-based method to determine the NDSRI level in a…

Acclaim™ Column Selection Guide Please refer to www.thermofisher.com/LCcolumns for more information Neutral Molecules General Applications Anionic Molecules Cationic Molecules Amphoteric/ Zwitterionic Molecules Mixtures of Neutral, Anionic, Cationic Molecules Surfactants Specific Applications Organic Acids Environmental Contaminants Vitamins Pharmacutical Counterions Industry High…