Application Note Studying Mobile Phases for HILIC UV/MS Analysis of Oligonucleotide Therapeutics including an siRNA Duplex, a Lipid Conjugated ASO, and a CRISPR sgRNA Szabolcs Fekete, Makda Araya, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation Abstract Hydrophilic interaction liquid chromatography…
Klíčová slova
hilic, oligonucleotide, acquity, mobile, sgrna, crispr, premier, mecn, solvent, mismatch, denaturing, conjugated, uplc, phase, bicarbonate