Residual host cell protein analysis of NISTmAb: From simplified sample preparation to reliable results

Confident LC-MS Identification of Low ppm Host Cell Proteins (HCPs) in Biotherapeutic Monoclonal Antibodies Amy J Claydon1, Phil Widdowson1, Andrew Williamson2, and Min Du3, Thermo Fisher Scientific, 1Runcorn, UK, 2Hemel Hempstead, UK, 3Cambridge, MA, USA Label-free quantification of NISTmAb HCPs…

Increasing sensitivity of high throughput host cell protein analysis on a novel highresolution accurate mass platform Eugen Damoc1; Tabiwang N. Arrey1; Anna Pashkova1; Eduard Denisov1; Kai Scheffler2; Kristina Srzentić3 1Thermo Fisher Scientific (Bremen) GmbH, Bremen, Germany; 2Thermo Fisher Scientific, Germering,…

APPLICATION NOTE 21918 Easy, fast and reproducible analysis of host cell protein (HCP) in monoclonal antibody preparations Authors Giorgio Oliviero1, Ken Cook 2, Kai Scheffler3, Florian Füssl1, Jonathan Bones1 1National Institute for Bioprocessing Research and Training, Dublin, Ireland; 2Thermo Fisher…

Biopharma Protein solutions eBook Protein therapeutics: At a glance Protein therapeutics are a type of biotherapeutics derived from genetically engineered human proteins. They offer several advantages over small-molecule drugs, allowing for more precise targeting of complex functions. Compared to chemical…