Figure out aggregation early: simultaneous, independent measurements of B22 and kD on Uncle

APPLICATION NOTE Assess aggregation risk at higher protein concentrations with G22 Introduction Weak, nonspecific interactions between protein molecules can have a large impact on colloidal stability during the development of protein-based drugs. The diffusion interaction parameter (kD) and the second…

Tech Note Meet Our Uncle: 12 Stability Applications on One Platform Uncle is an all-in-one stability platform that enables twelve different applications with one instrument. Fluorescence, static light scattering (SLS) and dynamic light scattering (DLS) detec­ tion methods are used…

Application Note Uncle sets a new benchmark for protein characterization Introduction The monoclonal antibody reference material distributed by the National Institute of Standards and Technology (NIST) has been extensively characterized by many researchers, and has become an excellent standard for…

APPLICATION NOTE Spot aggregation early with B22 and kD on Stunner Introduction Biopharmaceuticals are trending towards highconcentration therapeutics, but with higher concentrations also comes an increased risk of protein aggregation. The right formulation can reduce that risk, making high-throughput screening…