Meet Our Uncle: 12 Stability Applications on One Platform

One-stop stability Cracking stability using a pile of one-trick, sample-hungry tools is a ton of work. Uncle combines 3 different measurement modes — fluorescence, SLS and DLS. So you can crank out all your data in just a few hours,…

Application Note Uncle sets a new benchmark for protein characterization Introduction The monoclonal antibody reference material distributed by the National Institute of Standards and Technology (NIST) has been extensively characterized by many researchers, and has become an excellent standard for…

APPLICATION NOTE Meet Aunty – the Queen of protein stability Introduction Aunty is the fastest, highest throughput protein stability platform on the planet (Figure 1). Other stability methods each have their drawbacks: some are slow, others don’t give the full…

APPLICATION NOTE Assess aggregation risk at higher protein concentrations with G22 Introduction Weak, nonspecific interactions between protein molecules can have a large impact on colloidal stability during the development of protein-based drugs. The diffusion interaction parameter (kD) and the second…