Meet Aunty – the Queen of protein stability

APPLICATION NOTE Conquer ADC stability characterization with Aunty Introduction Conjugating potent cytotoxic payloads to monoclonal antibodies results in powerful anti-cancer therapeutics, but the resulting antibody-drug conjugates (ADCs) have unique stability challenges.1 Attaching a hydrophobic small molecule drug to a hydrophilic…

Dominate protein stability Aunty is the fastest and highest throughput protein stability characterization tool on the planet. Period. With unrivaled fluorescence, static light scattering and dynamic light scattering skills, Aunty blasts through thermal melting and aggregation experiments — reading an…

Tech Note Meet Our Uncle: 12 Stability Applications on One Platform Uncle is an all-in-one stability platform that enables twelve different applications with one instrument. Fluorescence, static light scattering (SLS) and dynamic light scattering (DLS) detec­ tion methods are used…

One-stop stability Cracking stability using a pile of one-trick, sample-hungry tools is a ton of work. Uncle combines 3 different measurement modes — fluorescence, SLS and DLS. So you can crank out all your data in just a few hours,…