Get the whole story: combine Tm and Tagg with sizing and polydispersity on Uncle

Application Note Uncle sets a new benchmark for protein characterization Introduction The monoclonal antibody reference material distributed by the National Institute of Standards and Technology (NIST) has been extensively characterized by many researchers, and has become an excellent standard for…

One-stop stability Cracking stability using a pile of one-trick, sample-hungry tools is a ton of work. Uncle combines 3 different measurement modes — fluorescence, SLS and DLS. So you can crank out all your data in just a few hours,…

Application Note Multi-day biologics stability experiments with Uncle Introduction 300 Thermal ramp stability measurements (Tm and Tagg) are well-established methods to quickly rank order the stability of protein constructs and formulations. Ranking may be more difficult if Tm or Tagg…

Tech Note Meet Our Uncle: 12 Stability Applications on One Platform Uncle is an all-in-one stability platform that enables twelve different applications with one instrument. Fluorescence, static light scattering (SLS) and dynamic light scattering (DLS) detec­ tion methods are used…