Quantifying more with less: Implementing charged aerosol detection to improve drug safety

CUSTOMER APPLICATION NOTE 74011 Impurity analysis of gabapentin by HPLC-UV-CAD Authors: Ruben Pawellek, Adrian Leistner, Ulrike Holzgrabe Institute of Pharmacy, University of Wuerzburg, Germany Keywords: Gabapentin, impurity analysis, Vanquish Horizon Charged Aerosol Detector, Variable Wavelength Detector Application benefits • Simultaneous…

CUSTOMER APPLICATION NOTE 73761 Impurity analysis of L-aspartic acid and glycine by HPLC-UV-CAD Authors: Ruben Pawellek, Adrian Leistner, Ulrike Holzgrabe University of Wuerzburg, Germany Keywords: Amino acids, impurity analysis, ion pair chromatography, Vanquish Horizon Charged Aerosol Detector, Variable Wavelength Detector…

Table of contents Summary Overview Excipient function Measurement Charged Aerosol Detector Universal detection Uniform response Working principles (U)HPLC Systems with CAD Columns choice Excipients overview Adjuvants Amino acids Carbohydrates Counterions Nonionic surfactants Polyethylene glycol Proteins and excipients HPLC-Charged Aerosol Detection…

Application note | 002575 Pharma Analysis of impurities in topiramate by HPLC with charged aerosol detection and a single quadrupole mass spectrometer Application benefits Authors Xuepu Li , Sven Hackbusch , Min Du 1 2 3 • Thermo Scientific™ Chromeleon™…