Extractables Analysis of Nasal Spray Devices Using Gas Chromatography and High- Resolution Mass Spectrometry With Soft Ionization

EXTRACTABLES ANALYSIS OF NASAL SPRAY DEVICES USING GAS CHROMATOGRAPHY AND QUADRUPOLE TIME OF FLIGHT HIGH-RESOLUTION MASS SPECTROMETRY WITH SOFT IONIZATION Rachel Sanig, Hania Khoury-Hollins, Jayne Kirk, Lee Gethings, Richard Lock Waters Corporation, Altrincham Road, Wilmslow, Cheshire, SK9 4AX, UK INTRODUCTION…

SCREENING FOR EXTRACTABLES AND LEACHABLES IN NASAL SPRAY DEVICES USING HIGH-RESOLUTION MASS SPECTROMETRY COMBINED WITH A DATA INDEPENDENT INFORMATICS STRATEGY Richard Lock1, Rachel Sanig1, Lee Gethings1, Jayne Kirk1, Sarah Dowd1, Nicholas Morley2 Waters Corporation, UK1, Element Materials Technology, UK2 INTRODUCTION…

Extractables, Leachables, and Food Contact Materials Application Notebook Extractables, Leachables, and Food Contact Materials Testing The safety of pharmaceuticals, cosmetics, and foodstuffs may be compromised by chemical compounds in the various types of packaging and food contact materials (FCMs) that…

ADDRESSING THE CHALLENGES OF EXTRACTABLES AND LEACHABLES SCREENING USING HIGH-RESOLUTION QUADRUPOLE TIME OF FLIGHT Rachel Sanig1, Jayne Kirk1, Cristian Cojocariu1, Andrew Feilden2 Waters Corporation,, Altrincham Road, Wilmslow, Cheshire, SK9 4AX, UK1, Hall Analytical Laboratories Ltd., Waterside Court, 1 Crewe Road,…