Confident material selection in liquid chromatography instrumentation: The meaning of inertness

[ WHITE PAPER ] Low Adsorption UPLC Systems and Columns Based on MaxPeak High Performance Surfaces: The ACQUITY Premier Solution T. H. Walter, M. Trudeau, J. Simeone, P. Rainville, A. V. Patel, M. A. Lauber, J. Kellett, M. DeLano, K.…

Technical note | 004606 Pharma and biopharma LC-UV analysis of large RNA using an inert UHPLC system Authors Test benefits Katherine Lovejoy, Audrius Žvirblis, 1 2 • Increased sensitivity of metal-sensitive analytes such as adenosine 5'-(α,β-methylene) diphosphate (AMPcP). • Consistent,…

ANALYSIS OF OLIGONUCLEOTIDE IMPURITIES ON THE BIOACCORD LC-MS SYSTEM WITH ACQUITY PREMIER Catalin Doneanu1, Christopher Knowles2, Jonathan Fox2, Emma Harry2, Ying Qing Yu1, Joseph Fredette1, Ann Grey1 and Weibin Chen1 1 Waters Corporation, Milford, MA, USA; 2Waters Corporation, Wilmslow, UK;…

Application Note Analysis of Oligonucleotide Impurities on the BioAccord System with ACQUITY Premier Catalin E. Doneanu, Chris Knowles, Jonathan Fox, Emma Harry, Ying Qing Yu, Joseph Fredette, Weibin Chen Waters Corporation Abstract This application note demonstrates an automated, compliance-ready LC-MS…