Low Adsorption UPLC Systems and Columns Based on MaxPeak High Performance Surfaces: The ACQUITY Premier Solution

MaxPeak Premier Columns Small Molecule Application Notebook CONTENTS Introduction Non-Specific Adsorption: Unwanted Interactions................................................................................... 3 How Do Scientists Solve This Problem Today?......................................................................................... 4 Precision Chemistry for Particles and Surfaces........................................................................................ 5 Fundamentals Waters™ Premier Standards to Investigate the Inertness of Chromatographic Systems....................................................................................................................................7…

Application Note PREMIER Standards to Investigate the Inertness of Chromatographic Surfaces Amit Patel, Jennifer Simeone, Susan C. Rzewuski, Moon Chul Jung, Matthew A. Lauber Waters Corporation Abstract Ensuring that instruments are in proper working order is a critical aspect of…

Application Note Improving Metal-Sensitive Analyte Recovery on Various LC Systems Using MaxPeak Premier Columns Kenneth D. Berthelette, Jennifer M. Nguyen, Kim Haynes, Amit Patel Waters Corporation Abstract Metal adsorption can be a significant problem in LC analysis, particularly for highly…

Technical note | 004606 Pharma and biopharma LC-UV analysis of large RNA using an inert UHPLC system Authors Test benefits Katherine Lovejoy, Audrius Žvirblis, 1 2 • Increased sensitivity of metal-sensitive analytes such as adenosine 5'-(α,β-methylene) diphosphate (AMPcP). • Consistent,…