Optimizing Mass Spectrometer Conditions to Accurately Determine Full/Empty AAV Ratios: A Sample Half-Full Approach

Application note | 003553 Native mass spectrometry Virus molecular weight and empty/full capsid ratio measurements on a Q Exactive UHMR mass spectrometer using Direct Mass Technology mode Authors Application benefits Kyle P. Bowen, Michael P. Goodwin, • Intact adeno-associated virus…

Customer note | 001049 Biotechnology Quantitative analysis of genome packaging in adeno-associated viruses using native MS Authors Key benefits Lisa Strasser1*, Tomos E. Morgan1, Felipe • Intact native mass spectrometry (MS) for the analysis of AAV-based viral vectors does not…

Setting the STORI Straight: Improved CDMS Results Via misSTORI Analysis Michael P. Goodwin, Kyle P. Bowen, Dmitry Grinfeld, Ping Yip, Michael W. Senko, Thermo Fisher Scientific, 355 River Oaks Parkway, San Jose, CA, USA, 95134 Abstract Purpose: Large ions often…

Go beyond what you thought possible with native MS Thermo Scientific Q Exactive UHMR Hybrid Quadrupole-Orbitrap mass spectrometer Gain deeper insight into native proteins Native mass spectrometry (MS) is a powerful technique for studying the structure of large protein complexes,…