Quantitative analysis of genome packaging in adeno-associated viruses using native MS

Application note | 003553 Native mass spectrometry Virus molecular weight and empty/full capsid ratio measurements on a Q Exactive UHMR mass spectrometer using Direct Mass Technology mode Authors Application benefits Kyle P. Bowen, Michael P. Goodwin, • Intact adeno-associated virus…

A Streamlined Workflow for the Characterisation and Relative Quantification of Recombinant Adeno-Associated Viruses using Charge Detection Mass Spectrometry Anisha Haris1, David Eatough1, Rebecca J D’Esposito2, Andrew Tudor1, Edvinas Karmonas1, David Bruton1, Keith Richardson1, Jakub Ujma1, Chris Wheeldon1, Alistair Schofield1, Michael…

Characterization of Adeno-Associated Viral assemblies on an Ultra-High Mass Range Hybrid QuadrupoleOrbitrap Mass Spectrometer Kristina Srzentić1, Eugen Damoc2, Marc Günder1 1Thermo Fisher Scientific, Reinach, Switzerland 2Thermo Fisher Scientific, Bremen, Germany ABSTRACT Purpose: Evaluate the performance of the Thermo Scientific™ Q…

ProPac™ 3R 3 μm IEX Separation and analysis of adeno-associated virus vectors using a 3 μm monodisperse strong anion exchange chromatography column Christof Mitterer1, Ke Ma2, Shane Bechler2, Shanhua Lin2. Thermo Fisher Scientific, 1 Langerwehe, Germany; 2 Sunnyvale, US Abstract…