Thermo Scientific Glycan Analysis for Biotherapeutics

Analytical solutions for biopharmaceutical characterization and control Your partner on every step of your journey Together we can address the challenges of biotherapeutic drug development Your molecules are complex Biotherapeutics such as monoclonal antibodies, biosimilars, antibody-drug conjugates, and nucleotide-based therapies…

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…

Towards a More Complete Glycome: Advances in Ion Chromatography-Mass Spectrometry (IC-MS) for Improved Separation and Analysis of Carbohydrates Neil G. Rumachik,* Tian Tian,* Yuanxue Hou, Charanjit Saini, Zoltan Szabo, Yan Liu, Chris Pohl, Thermo Fisher Scientific, 1228 Titan Way, Sunnyvale,…

Deanna Hurum, Lipika Basumallick, and Jeffrey Rohrer Thermo Fisher Scientific, Sunnyvale, CA, USA Key Words Prostate-Specific Antigen (PSA), Transferrin, N-Glycans, O-Glycans, Dionex CarboPac Column Introduction Changes in protein glycosylation are frequently studied in cancer research to identify potential biomarkers. Factors…