Analysis of hetero-oligomers with CG-MALS

AN3002: Understanding antibody and viral glycoprotein interactions using CG-MALS Kathryn M. Hastie, Ph.D., and Erica Ollmann Saphire, Ph.D., The Scripps Research Institute Summary Viral glycoproteins are often the only antigen found on the viral surface and, as such, are key…

W H I T E PA P E R WP3001: SEC-MALS and CG-MALS: Complementary Techniques to Characterize Protein-DNA Complexes Sophia Kenrick, Ph.D., Waters | Wyatt Technology Summary Interactions between proteins and nucleic acids often result in binding stoichiometries greater than…

A P P L I C AT I O N N O T E AN3008: Metacomplex Formation & Binding Affinity of Multivalent Binding Partners Sophia Kenrick, Ph.D. and Dan Some, Ph.D., Wyatt Technology Summary Multivalent binding plays a crucial role…

Light Scattering for the Masses ® Binding Affinity and Stoichiometry of a Multivalent Protein-aptamer Association Summary ecause proteins are often multimeric in their native state, the biomarker targets of many pharmaceuticals present multiple binding sites. In the case of monoclonal…