Hypersil GOLD Peptide column for reliable monitoring of glycopeptide variants in monoclonal antibodies by LC-UV-MS analysis

Technical note | 003308 Pharma / Biopharma Compliance-ready LC-UV-MS-based monitoring of antibody quality attributes using a single quadrupole mass spectrometer Authors Application benefits Sylvia Grosse1, Michaela S. Scherz1, • The Thermo Scientific™ ISQ™ EM Single Quadrupole Mass Spectrometer (SQMS) enables…

Biopharmaceuticals Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies Sylvia Grossea, Michaela S. Scherza, Jonathan Turnerb, Silvia Millán-Martínc, Sara Carilloc, Jonathan Bonesc, Kai Schefflera, Serdar Bilgesoyd aThermo Fisher Scientific, Germering, Germany, bThermo Fisher…

APPLICATION NOTE 21835 An automated high-throughput workflow for peptide mapping to monitor post-translational modifications (PTMs) of monoclonal antibodies Authors Silvia Millán-Martín, Craig Jakes, Giorgio Oliviero, Sara Carillo, Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing…

Analytical solutions for biopharmaceutical characterization and control Your partner on every step of your journey Together we can address the challenges of biotherapeutic drug development Your molecules are complex Biotherapeutics such as monoclonal antibodies, biosimilars, antibody-drug conjugates, and nucleotide-based therapies…